MyTron™ Magnetic Beads are rod-shaped superparamagnetic nanobeads with a particle size of <30 nm. Their surface is covalently conjugated with high-density streptavidin. Via biotin–streptavidin interaction (Kd ≈ 10⁻¹⁵ M), the beads can rapidly and specifically bind any biotinylated oligonucleotide probe to achieve hybrid capture of nucleic acid targets.
Benefiting from the ultra-high specific surface area conferred by the nanoscale particle size, this product exhibits a markedly higher probe binding capacity compared with conventional micron-sized magnetic beads 【11000–15000 pmol biotinylated oligonucleotides per mg beads】. The unique rod morphology and anti-aggregation design ensure fast and uniform magnetic response, with magnetic separation completed in <1 min.
The entire workflow (binding–washing–elution) can be finished within 10 minutes. It is compatible with qPCR, RT-qPCR, isothermal amplification and NGS library preparation and sequencing, and supports manual operation or integration with automated magnetic separation platforms.
